Seenu, a happy-go-lucky guy lives with his sister and brother-in-law. Seenu falls for Meghana, whom he meets at a wedding. However, Meghana is repulsive to love and Seenu's efforts don't work. The story takes a turn when Meghana is kidnapped by Liquor Shankar's men. Why do the goons pursue Meghana? How Seenu sets out to rescue her and help her deal with the goons forms the plot of Veedu Theda.