Blossom is an American sitcom broadcast on NBC from January 3, 1991, to May 22, 1995. The series was created by Don Reo, and starred Mayim Bialik as Blossom Russo, a teenager living with her father and two brothers. It … Mayim Bialik, Joey Lawrence, Michael Stoyanov, Jenna von Oy, Ted Wass, Barnard Hughes, Finola Hughes Added on Disney 2022-04-09.