Set in downtown New York in 1900, 'The Knick' is centered on the Knickerbocker Hospital and the groundbreaking surgeons, nurses and staff who work there, pushing the bounds of medicine in a time of astonishingly high mortality rates and zero … Clive Owen, André Holland, Jeremy Bobb, Juliet Rylance, Eve Hewson, Michael Angarano, Cara Seymour Added on HBO 2022-06-06. Youtube Trailer